30 Seconds Summary
The Creatine Handbook: Everything You Need to Know from Dosage to Timi

  • Creatine is an amino acid derivative popular among athletes for boosting strength and muscle mass, with a typical body synthesis rate of 1 gram per day.
  • Supplementation can increase muscle creatine stores by about 20%, significantly enhancing strength and fat-free mass, notably through improved ATP replenishment during short, high-intensity activities.
  • The typical dosing protocol includes a 'loading' phase of 20-25g per day for 3-5 days followed by a maintenance dose of 3-5g per day. Loading speeds efficacy but is not mandatory.
  • Creatine has been studied extensively and is proven to be effective in increasing strength and muscle mass in conjunction with resistance training.
  • It is also beneficial for cognitive function, showing potential in improving memory and processing speed, especially in vegetarians and older adults.
  • Common forms of creatine include monohydrate, phosphate, and citrate, with monohydrate being the most researched and cost-effective.
  • Creatine is considered safe for healthy individuals, with some concerns about potential renal stress in those with preexisting conditions.
  • Enhanced effects can be obtained by consuming creatine with simple carbohydrates or protein, improving creatine retention in muscles.
  • Some individuals ('non-responders'), might not experience benefits from creatine due to naturally high stores or genetic factors.
  • Timing of intake might not be crucial, but post-workout supplementation is potentially more beneficial for muscle gains.

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Tiago Vasconcelos, RP Research Editor

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