30 Seconds Summary
Antioxidants for Lifters: A Review of the Evidence

  • Antioxidants are important for managing oxidative stress and reactive species like free radicals, which can damage cells but also serve crucial signaling and immune functions.
  • While the body naturally regulates antioxidants through endogenous systems and diet, exercise increases the production of reactive species, enhancing the need for a balance to prevent oxidative damage.
  • Research shows that antioxidant supplementation can enhance blood flow and may improve microvascular health during exercise, primarily through the stabilization of nitric oxide.
  • Short-term antioxidant supplementation does not consistently show improvements in exercise performance, and the effects vary depending on the type of antioxidant and the exercise modality.
  • Antioxidants like vitamin C and vitamin E, when supplemented in high doses, do not substantially improve exercise performance or training adaptations and may, in some cases, slightly impair them.
  • Emerging evidence suggests that dietary sources of antioxidants, like fruits and vegetables, provide sufficient amounts to support health without the risks associated with high-dose supplements.
  • The relationship between antioxidants and training adaptations is complex, with some antioxidants potentially interfering with the muscular adaptations from resistance training.
  • Studies indicate mixed results on the impact of antioxidants on muscle recovery and damage; some show benefits while others do not provide strong enough evidence of meaningful effects.
  • It's suggested that a diet rich in natural antioxidants is beneficial for health and exercise recovery without the potential drawbacks of high-dose supplementation.

Track & Plan Workouts
with Ease

  • Unlimited workout logs
  • Automatic volume tracking
  • Personalized programs
  • RPE support, rest timer, and more!
WorkoutWise Screenshot

Read Next

Research Spotlight: Resistance training boosts your antioxidant system more than vitamin D supplementation

The study reviewed is “Elastic resistance training is more effective than vitamin D3 supplementation in reducing oxidative stress and strengthen antioxidant enzymes in healthy men” by Kalvandi et al. (2021)

Stronger By Science

Greg Nuckols

Research Spotlight: Does Vitamin C enhance recovery?

The study reviewed is “Effects of vitamin C on oxidative stress, inflammation, muscle soreness, and strength following acute exercise: meta-analyses of randomized clinical trials” by Righi et al.

Stronger By Science

Eric Trexler

Not Another Boring Creatine Guide: Answers to FAQs and Lesser-Known Benefits

You know creatine is beneficial for strength and power output. But you probably aren’t familiar with these lesser-known benefits and effects…

Stronger By Science

Eric Trexler