30 Seconds SummaryResearch Spotlight: Caffeine directly affects muscle function
- Caffeine is a stimulant primarily affecting the central nervous system by binding to A1 and A2A adenosine receptors in the brain.
 - Research by Domaszewski et al reveals that caffeine may also directly influence muscle tissue, as shown in tests with professional handball players given 9mg/kg of caffeine.
 - Following caffeine ingestion, the study observed decreased contraction times and increased maximal displacement in muscle during electrically stimulated contractions, indicating a direct effect on muscle function.
 - These results support earlier findings (Mohr et al, 1998) indicating that caffeine enhances muscle function even in electrically stimulated, paralyzed muscles.
 - The study highlights the persistent effectiveness of caffeine on the muscles of well-trained, regular caffeine consumers, with no need for a withdrawal period before testing.
 - While these findings are significant, they do not yet fundamentally alter practical applications regarding caffeine use in athletic or fitness settings.
 
Stronger By Science
Eric Trexler
