30 Seconds SummaryResearch Spotlight: Casein ingestion doesn’t increase muscle connective tissue protein synthesis
- Intramuscular connective tissue is crucial for muscle function, and previous research showed whey protein could enhance its synthesis post-exercise.
 - A study with 36 men evaluated casein's impact on this synthesis during sleep after resistance training, comparing exercise only, protein only, and exercise plus protein groups.
 - Participants exercised with leg presses and extensions or rested, followed by a standardized high-protein diet and additional protein intake 3 hours before bedtime.
 - At bedtime, the groups receiving protein (PRO, EX + PRO) were given 30g of casein.
 - Results showed exercise increased connective tissue protein synthesis, but the addition of casein did not enhance this effect beyond the exercise itself.
 - Researchers suggest that either a higher dose of casein or a different protein might influence results, but the high-protein diet provided might already maximize synthesis.
 - The conclusion is that while a high-protein diet supports muscular adaptation, 30g of casein before sleep doesn’t significantly boost connective tissue synthesis post-exercise.
 
Stronger By Science
Malisa Nguyen
