30 Seconds Summary
The First Clear Evidence of Delayed Hypertrophic Supercompensation

  • The study reviewed, conducted by Bjørnsen et al. (2018), involved untrained subjects undergoing two blocks of high-frequency, low-load blood flow restriction (BFR) training, revealing patterns of delayed hypertrophic supercompensation in muscle growth and strength.
  • Immediate training effects showed decreased muscle fiber cross-sectional area (CSA) and strength, which later increased significantly above baseline levels well after training had ceased.
  • Muscle fiber CSA and overall muscle size had differing adaptation patterns; whole muscle size did not decrease initially like fiber CSA did and stopped increasing after training ended.
  • During the study, subjects exhibited increased satellite cell numbers and myonuclear addition, suggesting muscular adaptations at cellular levels.
  • Despite intensive training phases, muscle damage markers (like creatine kinase and myoglobin) returned to normal between blocks due to the repeated bout effect, highlighting that muscle could adapt to the stress of BFR training.
  • The study's results suggest potential for delayed supercompensation in muscle growth and strength following specific training methods, particularly those using BFR. However, outcomes like increased muscle size might not align with improvements in visible muscularity due to differences in measurements of fiber and whole muscle hypertrophy.
  • The findings also highlight considerable individual variability in response to BFR training, with some subjects showing significantly different results in muscle growth and strength changes.

Track & Plan Workouts
with Ease

  • Unlimited workout logs
  • Automatic volume tracking
  • Personalized programs
  • RPE support, rest timer, and more!
WorkoutWise Screenshot

Read Next

Obsession vs. focus

Continuing the theme of goal setting, tonight I want to talk about obsession vs. focus. Just to recap, first you want to set a goal (that’s objective and time-constrained). Next you want to have a plan to get there. For both of the first two steps, you need to be accountable to someone, whether i…

Stronger By Science

Greg Nuckols

Diet Tracking and Disordered Eating: Which Comes First?

A common concern is that quantitatively tracking dietary intake may give rise to disordered eating. A new RCT casts doubt on this idea.

Stronger By Science

Eric Trexler

5 Things I Learnt in my First Year of Online Personal Training

Online Personal Training has kicked off big time. Some think it is a life of luxury, others think it is baloney, I share with you my lessons from year one.

Revive Stronger

Steve Hall

Band-Resisted Pushups = Bench Press for strength gains? Plus, how useful is EMG?

First things first, please give this post a little time to get rolling. There are bits of it that are primarily for nerds like myself, but there are also directly actionable parts, so be patient while we get there. You may have heard of EMG before. EMG stands for Electromyography – essentially measu…

Stronger By Science

Greg Nuckols

The Ins And Outs of The Lightest 1,000lb Squat In History

The first question I always get about squatting 800, 900 and now 1,000 pounds is “Man what does that feel like?” The best way I know how to describe it is just a whole lot of squish! The biggest difference for me is that my balance gets much harder to keep, especially when thicker squat bars start w…

Renaissance Periodization

Dr. Derek Wilcox, Sport Nutrition Coach